You have to go all the way back to 1997's The Devil's Advocate to find a horror movie on Charlize Theron's CV (unless you count Reindeer Games). Given the mill she's put through on that film, it's not that surprising that she shied away from the genre subsequently, but that should be about to change, with the news that Theron has personally picked up the rights to Two Eyes Staring.
The original Dutch film, titled Zwart Water at home, was directed by Elbert van Strien, and written by van Strien and Paulo van Vliet. It's the story of a nine-year-old girl who discovers that her new best friend has some sinister connections to dark secrets in her family's past. You can check out the trailer here: it's not subtitled, but you'll get the gist.
Zwart Water opened in The Netherlands this spring. It hasn't had an international release so far, but played the European festival circuit, including Edinburgh, all summer. Theron clearly caught it somewhere and was impressed: she's setting the film up through her Denver & Delilah production company, and is apparently meeting with "A-List directors" as we speak.