Played by: Anthony Hopkins
Film(s): Hannibal (2001), Red Dragon (2002), The Silence Of The Lambs (1991)
Jonathan Demme's adaptation of Thomas Harris' serial killer novel is magnificent, but every time that Anthony Hopkins appears on screen, it becomes a fully-fledged masterpiece. His Hannibal Lecter is parceled out throughout the film, dispensed to us in, appropriately enough, bitesized chunks, offering sinister advice and wisdom to Jodie Foster's Clarice Starling. Hopkins played Lecter, the brilliant psychiatrist turned incarcerated cannibal, as part-bird, part-Dracula. The combination is unforgettable. There are still those who would lobby to have Brian Cox's Lecktor, from Michael Mann's Manhunter, recognised as the best screen iteration of Hannibal, but it's the Oscar-winning, iconic, endlessly quoted Hopkins who gleefully sank his teeth into the zeitgeist. Let's hope he washed it down with a nice chianti.